ABSTRACT
This study was carried out at both Departments of Medicine and Radiotherapy and Nuclear Medicine Ain Shams University Hospitals between January, 1992 and February 1993. It included 2 groups. The first group consisted of 20 patients having criteria suggestive of intrinsic asthma [6 males and 14 females], their ages varied between [31 and 55 years]. The second group [controls] consisted of 20 volunteers who were not complaining of any allergic manifestations. The study showed that there was a positive correlation between total half life of plasma clearance of 99mTc-sulphur colloid and Forced expiratory volume in one second [FEVl] among intrinsic asthmatic patients but there was no significant difference between intrinsic asthmatic patients and control group as regard total half life of plasma clearance of 99mTc-sulphur colloid denoting that hepatic macrophages Kupffer cells are functionally active in the intrinsic asthmatic patients